It provides pictures and measurements of the microscopic fiber structures of the brain that enable language, social functioning and emotional, which can reveal differences that are not in those without autism, said Lange.Co-authors included: Molly Dubray, Alyson Froehlich, Brad Wright, P. Thomas Fletcher, all University of Utah, Erin Bigler of Brigham Young University, Nagesh Adluru, Alexander Alexander, and Jee-Eun Lee, University of Wisconsin, and Michael and Caitlin Ravichandran Froimowitz at Harvard and McLean.
By measuring six aspects of brain circuits, the test was able to correctly distinguish those who had been diagnosed with autism with 94 % accuracy.
Researchers at Harvard-affiliated McLean Hospital and the University of Utah have developed the best biological test to date. The test was able to diagnose the disease in individuals with high-functioning autism with 94 % accuracy. The study was published online in autism research.
The differences picked up on the study correlated with clinical symptoms that are part of the characteristics of autism, said Lainhart. There is less directional flow to and from the regions of the brain where there should be exchange of information, said Lange.
The research was funded by a $ 260,000 over four years of the American Heart Association National Scientist Development Grant and start-up funding and assistance from UAlbany. Chen received an award Grant-in-Aid American Heart Association beginning in July. The prize is $ 198 000 for three years to fund his research on potassium channels in cardiac hypokalemia background.
If the test demonstrates further success, could someday replace the current subjective diagnosis of autism, which is not a biological basis.
A group of people who had previously been diagnosed with high functioning autism with the standard system of scoring subjective. This system is based on the assessment of patients and their parents to question their functionality in a variety of areas, including language, social functioning and behavior. The second group was studied a control group of normally developing individuals.
A study of repeat with two different sets of subjects showed the same high level of performance.
The collaborative research group also study and develop the test results to be released in a year or two.
Future studies will focus on patients with autism of extreme gravity, the younger children and in patients with brain disorders such as disorders of language development and OCD, who do not have autism.
Source: http://www.pcaeg.org/?p=287
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